White truffle (Tuber Magnatum), an hypogeum fungus known since the mist of time and greatly appreciated for their culinary uses, is the rarest variety of truffles as it just grows in some extremely limited areas in Italy.
In nature truffles attract animalsusing volatile compounds. To date more than 200 different molecules have been identified from truffle species and some of these compounds are able to attract animals due to their similarities to some pheromones, this can explain why the white truffle aroma is so appreciated.
To investigate the effect that the white truffle phytocomplex can deliver to the skin in terms of gene expression modulation a microarray analysis was performed on keratinocytes and a human fibroblasts. Several groups of genes were modulated with some interesting down regulations of the metalloproteinases and up regulation of the extracellular matrix proteins, aquaporins, vitagenes and damaged protein degradation process.
The results obtained with instrumental and clinical dermatology examination assessments on 20 volunteers confirmed that W Tr-Active can acts as multi-functional anti-aging improving skin elasticity (+35%) and long term moisturization (+48%), reducing wrinkles (-12.8%) and eye bags (-14%) and delivering also a relevantfiller effect (+0.39mm).


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